CTNNA1 抗体 (AA 857-906)
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Quick Overview for CTNNA1 抗体 (AA 857-906) (ABIN1533220)
抗原
See all CTNNA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 857-906
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原理
- Catenin-α E/N Antibody
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特异性
- Catenin-α E/N Polyclonal Antibody detects endogenous levels of Catenin-α E/N protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Catenin-alpha1. AA range:857-906
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
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别名
- Catenin-Alpha1
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背景
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Synonyms: CTNNA1, Catenin alpha-1, Alpha E-catenin, Cadherin-associated protein, Renal carcinoma antigen NY-REN-13, CTNNA2, CAPR, Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein
Background: catenin alpha 1(CTNNA1) Homo sapiens This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016],
Gene Name: CTNNA1/CTNNA2
Protein Name: Catenin alpha-1/2
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分子量
- 100 kDa
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基因ID
- 1495, 1496
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OMIM
- 116805
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UniProt
- P35221
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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