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SPHK2 抗体 (AA 580-629)

The 兔 多克隆 anti-SPHK2 antibody is suitable to detect SPHK2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1533192
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SPHK2 抗体 (AA 580-629) (ABIN1533192)

抗原

See all SPHK2 抗体
SPHK2 (Sphingosine Kinase 2 (SPHK2))

适用

人, 小鼠, 大鼠

宿主

  • 67
  • 2
兔

克隆类型

  • 69
多克隆

标记

  • 42
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPHK2 antibody is un-conjugated

应用范围

  • 58
  • 39
  • 35
  • 6
  • 5
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 12
    • 10
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 580-629

    原理

    SphK2 Antibody

    特异性

    SphK2 Polyclonal Antibody detects endogenous levels of SphK2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human SPHK2. AA range:580-629

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SPHK2 (Sphingosine Kinase 2 (SPHK2))

    别名

    SPHK2

    背景

    Synonyms: SPHK2, Sphingosine kinase 2, SK 2, SPK 2

    Background: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],

    Gene Name: SPHK2

    Protein Name: Sphingosine kinase 2

    分子量

    69 kDa

    基因ID

    56848

    OMIM

    607092

    UniProt

    Q9NRA0

    途径

    VEGF Signaling
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