HTRA2 抗体 (AA 181-230)
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北京 101111
Quick Overview for HTRA2 抗体 (AA 181-230) (ABIN1533174)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-230
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原理
- HtrA2 Antibody
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特异性
- HtrA2 Polyclonal Antibody detects endogenous levels of HtrA2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HtrA2. AA range:181-230
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亚型
- IgG
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应用备注
- Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HtrA2
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背景
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Synonyms: HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI
Background: programmed cell death 1(PDCD1) Homo sapiens This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],
Gene Name: HTRA2
Protein Name: Serine protease HTRA2 mitochondrial
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分子量
- 48 kDa
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OMIM
- 168600
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UniProt
- O43464
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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