Claudin 7 抗体 (AA 162-211)
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北京 101111
Quick Overview for Claudin 7 抗体 (AA 162-211) (ABIN1533163)
抗原
See all Claudin 7 (CLDN7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 162-211
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原理
- Claudin-7 Antibody
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特异性
- Claudin-7 Polyclonal Antibody detects endogenous levels of Claudin-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Claudin 7. AA range:162-211
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Claudin 7 (CLDN7)
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别名
- Claudin 7
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背景
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Synonyms: CLDN7, CEPTRL2, CPETRL2, Claudin-7, CLDN-7
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010],
Gene Name: CLDN7
Protein Name: Claudin-7
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分子量
- 22 kDa
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基因ID
- 1366
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OMIM
- 609131
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UniProt
- O95471
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途径
- Hepatitis C
抗原
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