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Caldesmon 抗体 (AA 725-774)

This 兔 多克隆 antibody specifically detects Caldesmon in WB 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1533158
发货至: 中国
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Quick Overview for Caldesmon 抗体 (AA 725-774) (ABIN1533158)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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人, 大鼠, 小鼠

宿主

  • 142
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兔

克隆类型

  • 106
  • 75
多克隆

标记

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This Caldesmon antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 725-774

    原理

    Caldesmon Antibody

    特异性

    Caldesmon Polyclonal Antibody detects endogenous levels of Caldesmon protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Caldesmon. AA range:725-774

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    Caldesmon

    背景

    Synonyms: CALD1, CAD, CDM, Caldesmon, CDM

    Background: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

    Gene Name: CALD1

    Protein Name: Caldesmon

    分子量

    93 kDa

    基因ID

    800

    OMIM

    114213

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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