Mps1 抗体 (AA 642-691)
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北京 101111
Quick Overview for Mps1 抗体 (AA 642-691) (ABIN1533117)
抗原
See all Mps1 (TTK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 642-691
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原理
- TTK Antibody
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特异性
- TTK Polyclonal Antibody detects endogenous levels of TTK protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TTK. AA range:642-691
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Mps1 (TTK)
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别名
- TTK
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背景
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Synonyms: TTK, MPS1, MPS1L1, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT
Background: TTK protein kinase(TTK) Homo sapiens This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
Gene Name: TTK
Protein Name: Dual specificity protein kinase TTK
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分子量
- 97 kDa
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基因ID
- 7272
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OMIM
- 604092
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UniProt
- P33981
抗原
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