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Mps1 抗体 (AA 642-691)

The 兔 多克隆 anti-Mps1 antibody is suitable to detect Mps1 in samples from 人 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1533117
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Mps1 抗体 (AA 642-691) (ABIN1533117)

抗原

See all Mps1 (TTK) 抗体
Mps1 (TTK)

适用

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人, 小鼠

宿主

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兔

克隆类型

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  • 9
多克隆

标记

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This Mps1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 642-691

    原理

    TTK Antibody

    特异性

    TTK Polyclonal Antibody detects endogenous levels of TTK protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human TTK. AA range:642-691

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Mps1 (TTK)

    别名

    TTK

    背景

    Synonyms: TTK, MPS1, MPS1L1, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT

    Background: TTK protein kinase(TTK) Homo sapiens This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],

    Gene Name: TTK

    Protein Name: Dual specificity protein kinase TTK

    分子量

    97 kDa

    基因ID

    7272

    OMIM

    604092

    UniProt

    P33981
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