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Vitamin D Receptor 抗体 (AA 181-230)

The 兔 多克隆 anti-Vitamin D Receptor antibody is suitable to detect Vitamin D Receptor in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1532791
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Vitamin D Receptor 抗体 (AA 181-230) (ABIN1532791)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This Vitamin D Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 181-230

    原理

    VDR Antibody

    特异性

    VDR Polyclonal Antibody detects endogenous levels of VDR protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Vitamin D Receptor. AA range:181-230

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    Vitamin D Receptor

    物质类

    Chemical

    背景

    Synonyms: VDR, NR1I1, Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

    Background: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011],

    Gene Name: VDR

    Protein Name: Vitamin D3 receptor

    分子量

    48 kDa

    基因ID

    7421

    OMIM

    277440

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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