GRF2 抗体 (AA 470-519)
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Quick Overview for GRF2 抗体 (AA 470-519) (ABIN1532724)
抗原
See all GRF2 (RAPGEF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-519
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原理
- C3G Antibody
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特异性
- C3G Polyclonal Antibody detects endogenous levels of C3G protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RAPGEF1. AA range:470-519
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
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别名
- RapGEF1
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背景
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Synonyms: RAPGEF1, GRF2, Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G
Background: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: RAPGEF1
Protein Name: Rap guanine nucleotide exchange factor 1
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分子量
- 120 kDa
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基因ID
- 2889
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OMIM
- 600303
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UniProt
- Q13905
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途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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