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IL-10RA 抗体 (AA 462-511)

The 兔 多克隆 anti-IL-10RA antibody is suitable to detect IL-10RA in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN1532686
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-10RA 抗体 (AA 462-511) (ABIN1532686)

抗原

See all IL-10RA (IL10RA) 抗体
IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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  • 1
多克隆

标记

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This IL-10RA antibody is un-conjugated

应用范围

  • 69
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 10
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    AA 462-511

    原理

    IL-10Rα Antibody

    特异性

    IL-10Rα Polyclonal Antibody detects endogenous levels of IL-10Rα protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human IL-10R alpha. AA range:462-511

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

    别名

    IL-10R alpha

    背景

    Synonyms: IL10RA, IL10R, Interleukin-10 receptor subunit alpha, IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA, CDw210a, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R1, CD antigen CD210

    Background: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009],

    Gene Name: IL10RA

    Protein Name: Interleukin-10 receptor subunit alpha

    分子量

    62 kDa

    基因ID

    3587

    OMIM

    146933

    UniProt

    Q13651

    途径

    Growth Factor Binding
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