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PDGFRB 抗体 (AA 991-1040)

The 兔 多克隆 anti-PDGFRB antibody is suitable to detect PDGFRB in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1532641
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDGFRB 抗体 (AA 991-1040) (ABIN1532641)

抗原

See all PDGFRB 抗体
PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This PDGFRB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
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    AA 991-1040

    原理

    PDGFR-β Antibody

    特异性

    PDGFR-β Polyclonal Antibody detects endogenous levels of PDGFR-β protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human PDGFR beta. AA range:991-1040

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

    别名

    PDGFR beta

    背景

    Synonyms: PDGFRB, PDGFR, PDGFR1, Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-deri

    Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008],

    Gene Name: PDGFRB

    Protein Name: Platelet-derived growth factor receptor beta

    分子量

    123 kDa

    基因ID

    5159

    OMIM

    173410

    UniProt

    P09619

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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