Dematin 抗体 (AA 356-405)
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北京 101111
Quick Overview for Dematin 抗体 (AA 356-405) (ABIN1532596)
抗原
See all Dematin (EPB49) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 356-405
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原理
- Dematin Antibody
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特异性
- Dematin Polyclonal Antibody detects endogenous levels of Dematin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Dematin. AA range:356-405
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亚型
- IgG
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anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (C-Term) antibody
EPB49 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 1-383) antibodyEPB49 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (C-Term) antibodyEPB49 适用: 人, 小鼠, Cow WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 142-191) antibodyEPB49 适用: 人, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (pSer403) antibodyEPB49 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Ser345) antibodyEPB49 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
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别名
- Dematin
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背景
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Synonyms: EPB49; DMT; Dematin; Erythrocyte membrane protein band 4.9
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding di
Gene Name: EPB49
Protein Name: Dematin
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分子量
- 45 kDa
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基因ID
- 2039
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OMIM
- 125305
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UniProt
- Q08495
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途径
- Regulation of Actin Filament Polymerization
抗原
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