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Cyclin H 抗体 (AA 274-323)

The 兔 多克隆 anti-Cyclin H antibody is suitable to detect Cyclin H in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1532581
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cyclin H 抗体 (AA 274-323) (ABIN1532581)

抗原

See all Cyclin H (CCNH) 抗体
Cyclin H (CCNH)

适用

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人, 小鼠, 大鼠

宿主

  • 82
  • 17
兔

克隆类型

  • 61
  • 38
多克隆

标记

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This Cyclin H antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 14
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    • 2
    • 2
    • 2
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    • 1
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    AA 274-323

    原理

    Cyclin H Antibody

    特异性

    Cyclin H Polyclonal Antibody detects endogenous levels of Cyclin H protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Cyclin H. AA range:274-323

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Cyclin H (CCNH)

    别名

    Cyclin H

    背景

    Synonyms: CCNH, Cyclin-H, MO15-associated protein, p34, p37

    Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple t

    Gene Name: CCNH

    Protein Name: Cyclin-H

    分子量

    37 kDa

    基因ID

    902

    OMIM

    601953

    UniProt

    P51946

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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