CENPA 抗体 (AA 1-50)
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北京 101111
Quick Overview for CENPA 抗体 (AA 1-50) (ABIN1532568)
抗原
See all CENPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- CENP-A Antibody
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特异性
- CENP-A Polyclonal Antibody detects endogenous levels of CENP-A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Centromeric Protein A. AA range:1-50
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CENPA (Centromere Protein A (CENPA))
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背景
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Synonyms: CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A
Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes.This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015],
Gene Name: CENPA
Protein Name: Histone H3-like centromeric protein A
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分子量
- 15 kDa
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基因ID
- 1058
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OMIM
- 117139
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UniProt
- P49450
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途径
- Chromatin Binding, Maintenance of Protein Location
抗原
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