ICAM-3/CD50 抗体 (AA 484-533)
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北京 101111
Quick Overview for ICAM-3/CD50 抗体 (AA 484-533) (ABIN1532562)
抗原
See all ICAM-3/CD50 (ICAM3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 484-533
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原理
- CD50 Antibody
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特异性
- CD50 Polyclonal Antibody detects endogenous levels of CD50 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CD50/ICAM-3. AA range:484-533
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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别名
- CD50/ICAM-3
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背景
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Synonyms: ICAM3, Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, CD antigen CD50
Background: The protein encoded byThis gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Gene Name: ICAM3
Protein Name: Intercellular adhesion molecule 3
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分子量
- 59 kDa
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基因ID
- 3385
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OMIM
- 146631
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UniProt
- P32942
抗原
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