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L1CAM 抗体 (AA 1147-1196)

The 兔 多克隆 anti-L1CAM antibody (ABIN1532555) specifically detects L1CAM in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1532555
发货至: 中国
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Quick Overview for L1CAM 抗体 (AA 1147-1196) (ABIN1532555)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

适用

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人, 小鼠, 大鼠

宿主

  • 139
  • 48
  • 2
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兔

克隆类型

  • 100
  • 89
  • 1
多克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

  • 99
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1147-1196

    原理

    NCAM-L1 Antibody

    特异性

    NCAM-L1 Polyclonal Antibody detects endogenous levels of NCAM-L1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CD171/N-CAML1. AA range:1147-1196

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    CD171/N-CAML1

    背景

    Synonyms: L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD antigen CD171

    Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],

    Gene Name: L1CAM

    Protein Name: Neural cell adhesion molecule L1

    分子量

    140 kDa

    基因ID

    3897

    OMIM

    142623

    UniProt

    P32004

    途径

    Synaptic Membrane
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