L1CAM 抗体 (AA 1147-1196)
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北京 101111
Quick Overview for L1CAM 抗体 (AA 1147-1196) (ABIN1532555)
抗原
See all L1CAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1147-1196
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原理
- NCAM-L1 Antibody
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特异性
- NCAM-L1 Polyclonal Antibody detects endogenous levels of NCAM-L1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CD171/N-CAML1. AA range:1147-1196
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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别名
- CD171/N-CAML1
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背景
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Synonyms: L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD antigen CD171
Background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],
Gene Name: L1CAM
Protein Name: Neural cell adhesion molecule L1
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分子量
- 140 kDa
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基因ID
- 3897
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OMIM
- 142623
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UniProt
- P32004
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途径
- Synaptic Membrane
抗原
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