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PIN1 抗体 (AA 1-50)

The 兔 多克隆 anti-PIN1 antibody is suitable to detect PIN1 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN1532476
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PIN1 抗体 (AA 1-50) (ABIN1532476)

抗原

See all PIN1 抗体
PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

适用

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人, 小鼠, 大鼠

宿主

  • 132
  • 29
  • 2
  • 1
兔

克隆类型

  • 113
  • 51
多克隆

标记

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  • 1
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This PIN1 antibody is un-conjugated

应用范围

  • 133
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  • 9
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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 36
    • 15
    • 14
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Pin1 Antibody

    特异性

    Pin1 Polyclonal Antibody detects endogenous levels of Pin1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Pin1. AA range:1-50

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

    别名

    Pin1

    背景

    Synonyms: PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1

    Background: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds.This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011],

    Gene Name: PIN1

    Protein Name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

    分子量

    18 kDa

    基因ID

    5300

    OMIM

    601052

    UniProt

    Q13526
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