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Progesterone Receptor 抗体 (AA 261-310)

This 兔 多克隆 antibody specifically detects Progesterone Receptor in ELISA, IF, IHC (p) 和 ICC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN483013
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Progesterone Receptor 抗体 (AA 261-310) (ABIN483013)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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人, 大鼠, 小鼠

宿主

  • 206
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兔

克隆类型

  • 176
  • 109
  • 1
多克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 261-310

    原理

    PR Antibody

    特异性

    PR Polyclonal Antibody detects endogenous levels of PR protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Progesterone Receptor. AA range:261-310

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    Synonyms: PGR, NR3C3, Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3

    Background: tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

    Gene Name: PGR

    Protein Name: Progesterone receptor

    分子量

    98 kDa

    OMIM

    607311

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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