Progesterone Receptor 抗体 (AA 261-310)
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Quick Overview for Progesterone Receptor 抗体 (AA 261-310) (ABIN483013)
抗原
See all Progesterone Receptor (PGR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310
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原理
- PR Antibody
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特异性
- PR Polyclonal Antibody detects endogenous levels of PR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Progesterone Receptor. AA range:261-310
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亚型
- IgG
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应用备注
- Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Progesterone Receptor (PGR)
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别名
- Progesterone Receptor
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背景
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Synonyms: PGR, NR3C3, Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3
Background: tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Gene Name: PGR
Protein Name: Progesterone receptor
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分子量
- 98 kDa
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OMIM
- 607311
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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