PRKACA/PRKACB 抗体 (AA 166-215)
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北京 101111
Quick Overview for PRKACA/PRKACB 抗体 (AA 166-215) (ABIN1532391)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 166-215
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原理
- PKAα/β/γ cat Antibody
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特异性
- PKAα/β/γ cat Polyclonal Antibody detects endogenous levels of PKAα/β/γ cat protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PKA alpha/beta CAT. AA range:166-215
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亚型
- IgG
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anti-Protein Kinase A, alpha/beta (PRKACA/B) (N-Term) antibody
PRKACA/B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha/beta (PRKACA/B) (pThr197) antibodyPRKACA/B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha/beta (PRKACA/B) (N-Term) antibodyPRKACA/B 适用: 人, Pig, Cow, 犬, 绵羊, 马, 猴, 兔, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha/beta (PRKACA/B) (N-Term) antibodyPRKACA/B 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 绵羊, 马, 猴, 兔, 非洲爪蟾, 斑马鱼, Bat, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha/beta (PRKACA/B) (N-Term) antibodyPRKACA/B 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase A, alpha/beta (PRKACA/B) (AA 292-319), (C-Term) antibodyPRKACA/B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PRKACA/PRKACB (PRKACA/B) (Protein Kinase A, alpha/beta (PRKACA/B))
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别名
- PKA alpha/beta CAT
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背景
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Synonyms: PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; PRKACG; cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma
Background: This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern
Gene Name: PRKACA/PRKACB
Protein Name: cAMP-dependent protein kinase catalytic subunit alpha/beta
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分子量
- 40 kDa
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基因ID
- 5566, 5567
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OMIM
- 601639
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UniProt
- P17612
抗原
-
