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Aurora A 抗体 (AA 256-305)

This 兔 多克隆 antibody specifically detects Aurora A in WB, ELISA, IHC (p) 和 IF (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN482935
发货至: 中国
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Quick Overview for Aurora A 抗体 (AA 256-305) (ABIN482935)

抗原

See all Aurora A (AURKA) 抗体
Aurora A (AURKA) (Aurora Kinase A (AURKA))

适用

  • 162
  • 81
  • 42
  • 15
  • 8
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 162
  • 22
  • 2
  • 1
兔

克隆类型

  • 144
  • 42
多克隆

标记

  • 99
  • 12
  • 8
  • 8
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora A antibody is un-conjugated

应用范围

  • 151
  • 90
  • 70
  • 51
  • 40
  • 34
  • 15
  • 12
  • 10
  • 3
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 25
    • 13
    • 13
    • 13
    • 11
    • 9
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 256-305

    原理

    ARK-1 Antibody

    特异性

    ARK-1 Polyclonal Antibody detects endogenous levels of ARK-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Aurora Kinase. AA range:256-305

    亚型

    IgG
  • 应用备注

    Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    背景

    Synonyms: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, ARK-1, Aurora-related kinase 1, hARK1, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, Serine/threonin

    Background: mitogen-activated protein kinase kinase 3(MAP2K3) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: AURKA

    Protein Name: Aurora kinase A

    分子量

    45 kDa

    OMIM

    603072

    UniProt

    O14965

    途径

    Cell Division Cycle, Asymmetric Protein Localization
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