Opioid Receptor (AA 341-390) 抗体
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Quick Overview for Opioid Receptor (AA 341-390) 抗体 (ABIN1532207)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 341-390
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原理
- MOR-1 Antibody
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特异性
- MOR-1 Polyclonal Antibody detects endogenous levels of MOR-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Opioid Receptor. AA range:341-390
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亚型
- IgG
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anti-Opioid Receptor (AA 341-390), (pSer375) antibody
适用: 小鼠, 大鼠, 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Opioid Receptor (Ser375) antibody适用: 小鼠, 大鼠, 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Opioid Receptor
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背景
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Synonyms: OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOP
Background: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013],
Gene Name: OPRM1
Protein Name: Mu-type opioid receptor
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分子量
- 44 kDa
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基因ID
- 4988
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OMIM
- 600018
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UniProt
- P35372
抗原
-
