NCOA2 抗体 (pSer736)
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北京 101111
Quick Overview for NCOA2 抗体 (pSer736) (ABIN1532157)
抗原
See all NCOA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 702-751, pSer736
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原理
- GRIP-1 (phospho Ser736) Antibody
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特异性
- Phospho-GRIP-1 (S736) Polyclonal Antibody detects endogenous levels of GRIP-1 protein only when phosphorylated at S736.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NCoA2 around the phosphorylation site of Ser736. AA range:702-751
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亚型
- IgG
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anti-Nuclear Receptor Coactivator 2 (NCOA2) (AA 550-820) antibody
NCOA2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (C-Term) antibodyNCOA2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (C-Term) antibodyNCOA2 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (AA 706-739) antibodyNCOA2 适用: 人 WB 宿主: 兔 Polyclonal RB54073 unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (AA 1169-1203), (C-Term) antibodyNCOA2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50717 unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (AA 1431-1462) antibodyNCOA2 适用: 人 WB 宿主: 兔 Polyclonal RB53913 unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (C-Term) antibodyNCOA2 适用: 人, 小鼠 WB, IHC, IF, IP, IHC (p), PLA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (N-Term) antibodyNCOA2 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (AA 700-750) antibodyNCOA2 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 2 (NCOA2) (N-Term) antibodyNCOA2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
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别名
- NCoA2
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背景
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Synonyms: NCOA2, BHLHE75, TIF2, Nuclear receptor coactivator 2, NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
Background: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: NCOA2
Protein Name: Nuclear receptor coactivator 2
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分子量
- 159 kDa
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基因ID
- 10499
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OMIM
- 601993
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UniProt
- Q15596
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
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