Doublecortin 抗体 (pSer376)
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Quick Overview for Doublecortin 抗体 (pSer376) (ABIN1532140)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-365, pSer376
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原理
- Doublecortin (phospho Ser339) Antibody
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特异性
- Phospho-Doublecortin (S339) Polyclonal Antibody detects endogenous levels of Doublecortin protein only when phosphorylated at S339.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Doublecortin around the phosphorylation site of Ser376. AA range:330-365
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亚型
- IgG
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anti-Doublecortin (DCX) (AA 362-411) antibody
DCX 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Doublecortin (DCX) (AA 232-242) antibodyVerified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 362-411) antibodyDCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Doublecortin (DCX) (AA 69-81) antibodyVerified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 200-250) antibodyDCX 适用: 人, 小鼠 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR168J unconjugated Recombinant Antibody
anti-Doublecortin (DCX) (AA 1-360) antibodyDCX 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Doublecortin (DCX) (AA 11-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 108-360) antibodyDCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 107-137) antibodyDCX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15193 unconjugated
anti-Doublecortin (DCX) (pSer335) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Doublecortin (DCX)
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别名
- Doublecortin
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背景
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Synonyms: DCX; DBCN; LISX; Neuronal migration protein doublecortin; Doublin; Lissencephalin-X; Lis-X
Background: This gene encodes a member of the doublecortin family.The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo
Gene Name: DCX
Protein Name: Neuronal migration protein doublecortin
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分子量
- 44 kDa
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基因ID
- 1641
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OMIM
- 300067
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UniProt
- O43602
抗原
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