电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Claudin 6 抗体 (pTyr219)

This 兔 多克隆 antibody specifically detects Claudin 6 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1532133
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Claudin 6 抗体 (pTyr219) (ABIN1532133)

抗原

See all Claudin 6 (CLDN6) 抗体
Claudin 6 (CLDN6)

适用

  • 91
  • 26
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 73
  • 20
  • 5
  • 1
兔

克隆类型

  • 70
  • 25
  • 2
多克隆

标记

  • 42
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Claudin 6 antibody is un-conjugated

应用范围

  • 43
  • 27
  • 27
  • 25
  • 12
  • 11
  • 7
  • 7
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 25
    • 15
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 171-220, pTyr219

    原理

    Claudin-6 (phospho Tyr219) Antibody

    特异性

    Phospho-Claudin-6 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-6 protein only when phosphorylated at Y219.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Claudin 6 around the phosphorylation site of Tyr219. AA range:171-220

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Claudin 6 (CLDN6)

    别名

    Claudin 6

    背景

    Synonyms: CLDN6, Claudin-6, Skullin

    Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010],

    Gene Name: CLDN6

    Protein Name: Claudin-6

    分子量

    23 kDa

    基因ID

    9074

    UniProt

    P56747

    途径

    Hepatitis C
You are here: