SNRPE 抗体 (pThr753)
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北京 101111
Quick Overview for SNRPE 抗体 (pThr753) (ABIN1532127)
抗原
See all SNRPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 717-766, pThr753
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原理
- Raf-B (phospho Thr753) Antibody
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特异性
- Phospho-Raf-B (T753) Polyclonal Antibody detects endogenous levels of Raf-B protein only when phosphorylated at T753.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human B-Raf around the phosphorylation site of Thr753. AA range:717-766
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
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别名
- B-Raf
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背景
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Synonyms: BRAF, BRAF1, RAFB1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1
Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008],
Gene Name: BRAF
Protein Name: Serine/threonine-protein kinase B-raf
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分子量
- 84 kDa
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基因ID
- 673
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OMIM
- 114500
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UniProt
- P15056
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途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
抗原
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