CBX3 抗体 (pSer93)
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北京 101111
Quick Overview for CBX3 抗体 (pSer93) (ABIN1532101)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-108, pSer93
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原理
- HP1γ (phospho Ser93) Antibody
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特异性
- Phospho-HP1γ (S93) Polyclonal Antibody detects endogenous levels of HP1γ protein only when phosphorylated at S93.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HP1 gamma around the phosphorylation site of Ser93. AA range:59-108
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- HP1 gamma
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背景
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Synonyms: CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein
Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane.The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011],
Gene Name: CBX3
Protein Name: Chromobox protein homolog 3
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分子量
- 20 kDa
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基因ID
- 11335, 653972
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OMIM
- 604477
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UniProt
- Q13185
抗原
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