ICK 抗体 (pTyr159)
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北京 101111
Quick Overview for ICK 抗体 (pTyr159) (ABIN1532046)
抗原
See all ICK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-174, pTyr159
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原理
- Intestinal Cell Kinase (phospho Tyr159) Antibody
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特异性
- Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ICK around the phosphorylation site of Tyr159. AA range:125-174
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ICK (Intestinal Cell (MAK-Like) Kinase (ICK))
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别名
- ICK
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背景
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Synonyms: ICK, KIAA0936, Serine/threonine-protein kinase ICK, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRK
Background: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases.This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008],
Gene Name: ICK
Protein Name: Serine/threonine-protein kinase ICK
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分子量
- 71 kDa
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基因ID
- 22858
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OMIM
- 612325
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UniProt
- Q9UPZ9
抗原
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