LIMK2 抗体 (pSer283)
Our Local Distributor
北京 101111
Quick Overview for LIMK2 抗体 (pSer283) (ABIN1532018)
抗原
See all LIMK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 249-298, pSer283
-
原理
- LIMK-2 (phospho Ser283) Antibody
-
特异性
- Phospho-LIMK-2 (S283) Polyclonal Antibody detects endogenous levels of LIMK-2 protein only when phosphorylated at S283.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human LIMK2 around the phosphorylation site of Ser283. AA range:249-298
-
亚型
- IgG
-
-
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibody
LIMK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2H2-E11 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (pThr505) antibodyLIMK2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) antibodyLIMK2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 570-599), (C-Term) antibodyLIMK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB42813 unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-240) antibodyLIMK2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (Ser283) antibodyLIMK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 1-686) antibodyLIMK2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (AA 181-193) antibodyVerified LIMK2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-LIM Domain Kinase 2 (LIMK2) (pSer283) antibodyLIMK2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- LIMK2 (LIM Domain Kinase 2 (LIMK2))
-
别名
- LIMK2
-
背景
-
Synonyms: LIMK2, LIM domain kinase 2, LIMK-2
Background: There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: LIMK2
Protein Name: LIM domain kinase 2
-
分子量
- 72 kDa
-
基因ID
- 3985
-
OMIM
- 601988
-
UniProt
- P53671
抗原
-
