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Ezrin 抗体 (pTyr146)

The 兔 多克隆 anti-Ezrin antibody is suitable to detect Ezrin in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1532009
发货至: 中国
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Quick Overview for Ezrin 抗体 (pTyr146) (ABIN1532009)

抗原

See all Ezrin (EZR) 抗体
Ezrin (EZR)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Ezrin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 111-160, pTyr146

    原理

    Ezrin (phospho Tyr146) Antibody

    特异性

    Phospho-Ezrin (Y146) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y146.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr146. AA range:111-160

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Ezrin (EZR)

    别名

    Ezrin

    背景

    Synonyms: EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81

    Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: EZR

    Protein Name: Ezrin

    分子量

    69 kDa

    基因ID

    7430

    OMIM

    123900

    UniProt

    P15311

    途径

    Maintenance of Protein Location
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