Ezrin 抗体 (pTyr146)
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Quick Overview for Ezrin 抗体 (pTyr146) (ABIN1532009)
抗原
See all Ezrin (EZR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-160, pTyr146
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原理
- Ezrin (phospho Tyr146) Antibody
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特异性
- Phospho-Ezrin (Y146) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y146.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Ezrin around the phosphorylation site of Tyr146. AA range:111-160
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Ezrin (EZR)
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别名
- Ezrin
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背景
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Synonyms: EZR, VIL2, Ezrin, Cytovillin, Villin-2, p81
Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: EZR
Protein Name: Ezrin
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分子量
- 69 kDa
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基因ID
- 7430
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OMIM
- 123900
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UniProt
- P15311
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途径
- Maintenance of Protein Location
抗原
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