Merlin 抗体 (pSer518)
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北京 101111
Quick Overview for Merlin 抗体 (pSer518) (ABIN1531906)
抗原
See all Merlin (NF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 485-534, pSer518
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原理
- NF2 (phospho Ser518) Antibody
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特异性
- Phospho-NF2 (S518) Polyclonal Antibody detects endogenous levels of NF2 protein only when phosphorylated at S518.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Merlin around the phosphorylation site of Ser518. AA range:485-534
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亚型
- IgG
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anti-Neurofibromin 2 (NF2) (AA 477-576) antibody
NF2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) antibodyKD Validated NF2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2620 unconjugated Recombinant Antibody
anti-Neurofibromin 2 (NF2) (AA 15-565) antibodyNF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 230-414) antibodyNF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (pSer518) antibodyNF2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 65-95), (N-Term) antibodyNF2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19187 unconjugated
anti-Neurofibromin 2 (NF2) (AA 30-239) antibodyNF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 30-311) antibodyNF2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (AA 1-507) antibodyNF2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Neurofibromin 2 (NF2) (C-Term) antibodyNF2 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Merlin (NF2) (Neurofibromin 2 (NF2))
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别名
- Merlin
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背景
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Synonyms: NF2, SCH, Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin
Background: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008],
Gene Name: NF2
Protein Name: Merlin
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分子量
- 69 kDa
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基因ID
- 4771
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OMIM
- 101000
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UniProt
- P35240
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途径
- Cell-Cell Junction Organization
抗原
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