MEF2A 抗体 (pThr319)
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Quick Overview for MEF2A 抗体 (pThr319) (ABIN1531901)
抗原
See all MEF2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 296-345, pThr319
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原理
- MEF-2 (phospho Thr319) Antibody
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特异性
- Phospho-MEF-2 (T319) Polyclonal Antibody detects endogenous levels of MEF-2 protein only when phosphorylated at T319.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Thr319. AA range:296-345
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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别名
- MEF2A
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背景
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Synonyms: MEF2A, MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1
Background: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010],
Gene Name: MEF2A
Protein Name: Myocyte-specific enhancer factor 2A
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分子量
- 54 kDa
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基因ID
- 4205
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OMIM
- 600660
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UniProt
- Q02078
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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