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MARCKS 抗体 (pSer163)

The 兔 多克隆 anti-MARCKS antibody (ABIN1531899) specifically detects MARCKS in ELISA, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1531899
发货至: 中国
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Quick Overview for MARCKS 抗体 (pSer163) (ABIN1531899)

抗原

See all MARCKS 抗体
MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

适用

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  • 1
人, 大鼠, 小鼠

宿主

  • 128
  • 6
  • 1
  • 1
兔

克隆类型

  • 130
  • 6
多克隆

标记

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This MARCKS antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 28
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    • 1
    • 1
    • 1
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    • 1
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    AA 136-185, pSer163

    原理

    MARCKS (phospho Ser163) Antibody

    特异性

    Phospho-MARCKS (S163) Polyclonal Antibody detects endogenous levels of MARCKS protein only when phosphorylated at S163.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MARCKS around the phosphorylation site of Ser163. AA range:136-185

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

    别名

    MARCKS

    背景

    Synonyms: MARCKS, MACS, PRKCSL, Myristoylated alanine-rich C-kinase substrate, MARCKS, Protein kinase C substrate, 80 kDa protein, light chain, 80K-L protein, PKCSL

    Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008],

    Gene Name: MARCKS

    Protein Name: Myristoylated alanine-rich C-kinase substrate

    分子量

    31 kDa

    基因ID

    4082

    OMIM

    177061

    UniProt

    P29966
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