DRP2 抗体 (pThr514)
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Quick Overview for DRP2 抗体 (pThr514) (ABIN1531738)
抗原
See all DRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 480-529, pThr514
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原理
- CRMP-2 (phospho Thr514) Antibody
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特异性
- Phospho-CRMP-2 (T514) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at T514.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human DRP-2 around the phosphorylation site of Thr514. AA range:480-529
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亚型
- IgG
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anti-Dystrophin Related Protein 2 (DRP2) (AA 463-492) antibody
DRP2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 33CT11-40-3 unconjugated
anti-Dystrophin Related Protein 2 (DRP2) (AA 697-833) antibodyDRP2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DRP2 (Dystrophin Related Protein 2 (DRP2))
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别名
- DRP-2
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背景
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Synonyms: DPYSL2; CRMP2; ULIP2; Dihydropyrimidinase-related protein 2; DRP-2; Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2
Background: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
Gene Name: DPYSL2
Protein Name: Dihydropyrimidinase-related protein 2
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分子量
- 62 kDa
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基因ID
- 1808
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OMIM
- 602463
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UniProt
- Q16555
抗原
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