TERT 抗体 (pSer227)
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北京 101111
Quick Overview for TERT 抗体 (pSer227) (ABIN1531729)
抗原
See all TERT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 196-245, pSer227
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原理
- TERT (phospho Ser227) Antibody
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特异性
- Phospho-TERT (S227) Polyclonal Antibody detects endogenous levels of TERT protein only when phosphorylated at S227.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Telomerase around the phosphorylation site of Ser227. AA range:196-245
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亚型
- IgG
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anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibody
TERT 适用: 人 WB, ELISA, IHC, IF, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibodyTERT 适用: 人 WB, ELISA, IHC, IF, IP, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 601-750) antibodyTERT 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 1029-1132) antibodyTERT 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3H2C12 unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 597-611) antibodyVerified TERT 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (pTyr707) antibodyTERT 适用: 人 IF, DB 宿主: 兔 Polyclonal RB16840 unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 627-656) antibodyTERT 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) antibodyTERT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) antibodyTERT 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1945 unconjugated Recombinant Antibody
anti-Telomerase Reverse Transcriptase (TERT) (AA 642-974) antibodyTERT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TERT (Telomerase Reverse Transcriptase (TERT))
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别名
- Telomerase
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背景
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Synonyms: TERT, EST2, TCS1, TRT, Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, TP2
Background: Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative sp
Gene Name: TERT
Protein Name: Telomerase reverse transcriptase
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分子量
- 126 kDa
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基因ID
- 7015
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OMIM
- 127550
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UniProt
- O14746
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途径
- Telomere Maintenance
抗原
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