PIKFYVE 抗体 (pSer307)
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北京 101111
Quick Overview for PIKFYVE 抗体 (pSer307) (ABIN1531726)
抗原
See all PIKFYVE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 273-322, pSer307
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原理
- PIP5KIII (phospho Ser307) Antibody
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特异性
- Phospho-PIP5KIII (S307) Polyclonal Antibody detects endogenous levels of PIP5KIII protein only when phosphorylated at S307.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PIP5K around the phosphorylation site of Ser307. AA range:273-322
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亚型
- IgG
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anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) antibody
PIKFYVE 适用: 人 ELISA, WB, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 6C7 unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1531-1561) antibodyPIKFYVE 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5311 unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) antibodyPIKFYVE 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (N-Term) antibodyPIKFYVE 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1819-2098) antibodyPIKFYVE 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 342-451) antibodyPIKFYVE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) antibodyPIKFYVE 适用: Various Species WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (N-Term) antibodyPIKFYVE 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (AA 1-451) antibodyPIKFYVE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE) (N-Term) antibodyPIKFYVE 适用: 人, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
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别名
- PIP5K
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背景
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Synonyms: PIKFYVE, KIAA0981, PIP5K3, 1-phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase, FYVE finger-containing phosphoinositide kinase, PIKfyve, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type
Background: Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring.This gene encodes an enzyme (PIKfyve, also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKf
Gene Name: PIKFYVE
Protein Name: 1-phosphatidylinositol 3-phosphate 5-kinase
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分子量
- 237 kDa
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基因ID
- 200576
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OMIM
- 121850
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UniProt
- Q9Y2I7
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途径
- Inositol Metabolic Process
抗原
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