Integrin beta 4 抗体 (pTyr1510)
Our Local Distributor
北京 101111
Quick Overview for Integrin beta 4 抗体 (pTyr1510) (ABIN1531676)
抗原
See all Integrin beta 4 (ITGB4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1481-1530, pTyr1510
-
原理
- Integrin β4 (phospho Tyr1510) Antibody
-
特异性
- Phospho-Integrin β4 (Y1510) Polyclonal Antibody detects endogenous levels of Integrin β4 protein only when phosphorylated at Y1510.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human ITGB4 around the phosphorylation site of Tyr1510. AA range:1481-1530
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Integrin beta 4 (ITGB4)
-
别名
- ITGB4
-
背景
-
Synonyms: ITGB4, Integrin beta-4, GP150, CD antigen CD104
Background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth.This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: ITGB4
Protein Name: Integrin beta-4
-
分子量
- 202 kDa
-
基因ID
- 3691
-
OMIM
- 147557
-
UniProt
- P16144
-
途径
- Integrin Complex
抗原
-