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Integrin beta 4 抗体 (pTyr1510)

The 兔 多克隆 anti-Integrin beta 4 antibody is suitable to detect Integrin beta 4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1531676
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Integrin beta 4 抗体 (pTyr1510) (ABIN1531676)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

  • 142
  • 63
  • 23
  • 4
  • 4
人, 小鼠, 大鼠

宿主

  • 97
  • 55
  • 9
  • 2
兔

克隆类型

  • 83
  • 80
多克隆

标记

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This Integrin beta 4 antibody is un-conjugated

应用范围

  • 98
  • 81
  • 67
  • 52
  • 43
  • 28
  • 22
  • 15
  • 13
  • 13
  • 8
  • 7
  • 7
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 26
    • 15
    • 12
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1481-1530, pTyr1510

    原理

    Integrin β4 (phospho Tyr1510) Antibody

    特异性

    Phospho-Integrin β4 (Y1510) Polyclonal Antibody detects endogenous levels of Integrin β4 protein only when phosphorylated at Y1510.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ITGB4 around the phosphorylation site of Tyr1510. AA range:1481-1530

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    ITGB4

    背景

    Synonyms: ITGB4, Integrin beta-4, GP150, CD antigen CD104

    Background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth.This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: ITGB4

    Protein Name: Integrin beta-4

    分子量

    202 kDa

    基因ID

    3691

    OMIM

    147557

    UniProt

    P16144

    途径

    Integrin Complex
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