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HRS (HRS) (AA 301-350), (pTyr334) 抗体

The 兔 多克隆 anti-HRS antibody is suitable to detect HRS in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1531658
发货至: 中国
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Quick Overview for HRS (HRS) (AA 301-350), (pTyr334) 抗体 (ABIN1531658)

抗原

See all HRS 抗体
HRS

适用

人, 小鼠, 大鼠

宿主

  • 9
  • 2
兔

克隆类型

  • 9
  • 2
多克隆

标记

  • 11
非结合性

应用范围

  • 10
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-350, pTyr334

    原理

    Hrs (phospho Tyr334) Antibody

    特异性

    Phospho-Hrs (Y334) Polyclonal Antibody detects endogenous levels of Hrs protein only when phosphorylated at Y334.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334. AA range:301-350

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HRS

    别名

    HRS

    背景

    Synonyms: HGS, HRS, Hepatocyte growth factor-regulated tyrosine kinase substrate, Hrs, Protein pp110

    Background: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010],

    Gene Name: HGS

    Protein Name: Hepatocyte growth factor-regulated tyrosine kinase substrate

    分子量

    86 kDa

    基因ID

    9146

    OMIM

    604375

    UniProt

    O14964

    途径

    CXCR4-mediated Signaling Events, EGFR Downregulation
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