Vinculin 抗体 (pTyr821)
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Quick Overview for Vinculin 抗体 (pTyr821) (ABIN1531640)
抗原
See all Vinculin (VCL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 786-835, pTyr821
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原理
- Vinculin (phospho Tyr821) Antibody
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特异性
- Phospho-Vinculin (Y821) Polyclonal Antibody detects endogenous levels of Vinculin protein only when phosphorylated at Y821.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Vinculin around the phosphorylation site of Tyr821. AA range:786-835
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亚型
- IgG
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anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 2C6-1B5 unconjugated
anti-Vinculin (VCL) (AA 903-937) antibodyVCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55983 unconjugated
anti-Vinculin (VCL) (AA 879-1064) antibodyVCL 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vinculin (VCL) (AA 634-668) antibodyVCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55982 unconjugated
anti-Vinculin (VCL) (AA 174-322) antibodyVCL 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal VCL-2572 unconjugated
anti-Vinculin (VCL) (AA 174-322) antibodyVCL 适用: 人, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal VCL-2575 unconjugated
anti-Vinculin (VCL) (AA 767-1066) antibodyVCL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vinculin (VCL) (AA 1020-1134) antibodyVCL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vinculin (VCL) (AA 1016-1066) antibodyVCL 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Vinculin (VCL) (AA 12-39), (N-Term) antibodyVCL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15469 unconjugated
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Vinculin (VCL)
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别名
- Vinculin
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背景
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Synonyms: VCL, Vinculin, Metavinculin
Background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],
Gene Name: VCL
Protein Name: Vinculin
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分子量
- 123 kDa
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基因ID
- 7414
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OMIM
- 193065
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UniProt
- P18206
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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