GRK1 抗体 (pSer21)
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北京 101111
Quick Overview for GRK1 抗体 (pSer21) (ABIN1531605)
抗原
See all GRK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-55, pSer21
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原理
- GRK 1 (phospho Ser21) Antibody
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特异性
- Phospho-GRK 1 (S21) Polyclonal Antibody detects endogenous levels of GRK 1 protein only when phosphorylated at S21.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GRK1 around the phosphorylation site of Ser21. AA range:6-55
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))
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别名
- GRK1
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背景
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Synonyms: GRK1, RHOK, Rhodopsin kinase, RK, G protein-coupled receptor kinase 1
Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],
Gene Name: GRK1
Protein Name: Rhodopsin kinase
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分子量
- 63 kDa
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基因ID
- 6011
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OMIM
- 180381
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UniProt
- Q15835
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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