MAPK15 抗体 (pThr175, pTyr177)
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Quick Overview for MAPK15 抗体 (pThr175, pTyr177) (ABIN1531592)
抗原
See all MAPK15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-190, pThr175, pTyr177
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原理
- ERK 8 (phospho Thr175/Y177) Antibody
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特异性
- Phospho-ERK 8 (T175/Y177) Polyclonal Antibody detects endogenous levels of ERK 8 protein only when phosphorylated at T175/Y177.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ERK8 around the phosphorylation site of Thr175 and Tyr177. AA range:141-190
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 32-61), (N-Term) antibody
MAPK15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12573 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-95) antibodyMAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) antibodyMAPK15 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 小鼠 Monoclonal 8C6 unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-245) antibodyMAPK15 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 395-444) antibodyMAPK15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (pThr175), (pTyr177) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (Tyr877) antibodyMAPK15 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 15 (MAPK15) (AA 1-277) antibodyMAPK15 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))
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别名
- ERK8
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背景
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Synonyms: MAPK15, ERK7, ERK8, Mitogen-activated protein kinase 15, MAP kinase 15, MAPK 15, Extracellular signal-regulated kinase 7, ERK-7, Extracellular signal-regulated kinase 8, ERK-8
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The N-terminal region (1-20) is the minimal region necessary for ubiquitination and further proteosomal degradation.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation. Inhibited by dual specificity phosphatases, such as DUSP1.,function:In vitro, phosphorylates MBP.,PTM:Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme. Autophosphorylated on threonine and tyrosine residues in vitro.,PTM:Ubiquitinated. Ubiquitination may allow its tight kinase activity regulation and rapid turnover. May be ubiquitinated by a SCF E3 ligase.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CSK/c-Src, ABL1, RET and TGFB1I1.,tissue specificity:Widely expressed with a maximal expression in lung and kidney.,
Gene Name: MAPK15
Protein Name: Mitogen-activated protein kinase 15
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分子量
- 59 kDa
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基因ID
- 225689
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UniProt
- Q8TD08
抗原
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