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EPOR 抗体 (pTyr368)

The 兔 多克隆 anti-EPOR antibody is suitable to detect EPOR in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN482201
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for EPOR 抗体 (pTyr368) (ABIN482201)

抗原

EPOR (Erythropoietin Receptor (EPOR))

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This EPOR antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 341-390, pTyr368

    原理

    EpoR (phospho Tyr368) Antibody

    特异性

    Phospho-EpoR (Y368) Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Y368.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368. AA range:341-390

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    EPOR (Erythropoietin Receptor (EPOR))

    别名

    Epo-R

    背景

    Synonyms: EPOR, Erythropoietin receptor, EPO-R

    Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

    Gene Name: EPOR

    Protein Name: Erythropoietin receptor

    分子量

    55 kDa

    基因ID

    2057

    OMIM

    133100

    UniProt

    P19235

    途径

    JAK/STAT Signaling
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