EPOR 抗体 (pTyr368)
Our Local Distributor
北京 101111
Quick Overview for EPOR 抗体 (pTyr368) (ABIN1531589)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 341-390, pTyr368
-
原理
- EpoR (phospho Tyr368) Antibody
-
特异性
- Phospho-EpoR (Y368) Polyclonal Antibody detects endogenous levels of EpoR protein only when phosphorylated at Y368.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human Epo-R around the phosphorylation site of Tyr368. AA range:341-390
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- EPOR (Erythropoietin Receptor (EPOR))
-
别名
- Epo-R
-
背景
-
Synonyms: EPOR, Erythropoietin receptor, EPO-R
Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Gene Name: EPOR
Protein Name: Erythropoietin receptor
-
分子量
- 55 kDa
-
基因ID
- 2057
-
OMIM
- 133100
-
UniProt
- P19235
-
途径
- JAK/STAT Signaling
抗原
-