Cyclin H 抗体 (pThr315)
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北京 101111
Quick Overview for Cyclin H 抗体 (pThr315) (ABIN1531566)
抗原
See all Cyclin H (CCNH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 274-323, pThr315
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原理
- Cyclin H (phospho Thr315) Antibody
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特异性
- Phospho-Cyclin H (T315) Polyclonal Antibody detects endogenous levels of Cyclin H protein only when phosphorylated at T315.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cyclin H around the phosphorylation site of Thr315. AA range:274-323
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亚型
- IgG
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anti-Cyclin H (CCNH) (AA 1-110) antibody
CCNH 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) antibodyCCNH 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Cyclin H (CCNH) (AA 269-299), (C-Term) antibodyCCNH 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB14888 unconjugated
anti-Cyclin H (CCNH) (pThr315) antibodyCCNH 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 1-323) antibodyCCNH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin H (CCNH) (AA 221-323) antibodyCCNH 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin H (CCNH) antibodyCCNH 适用: 人 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-Cyclin H (CCNH) (AA 24-52), (N-Term) antibodyCCNH 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal RB14999 unconjugated
anti-Cyclin H (CCNH) (C-Term) antibodyCCNH 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, 兔, 马, Cow, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cyclin H (CCNH)
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别名
- Cyclin H
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背景
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Synonyms: CCNH, Cyclin-H, MO15-associated protein, p34, p37
Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple t
Gene Name: CCNH
Protein Name: Cyclin-H
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分子量
- 37 kDa
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基因ID
- 902
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OMIM
- 601953
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UniProt
- P51946
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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