CXCR4 抗体 (pSer339)
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北京 101111
Quick Overview for CXCR4 抗体 (pSer339) (ABIN1531564)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 303-352, pSer339
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原理
- Fusin (phospho Ser339) Antibody
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特异性
- Phospho-Fusin (S339) Polyclonal Antibody detects endogenous levels of Fusin protein only when phosphorylated at S339.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. AA range:303-352
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- CXCR4
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背景
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Synonyms: CXCR4, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD antigen CD184
Background: C-X-C motif chemokine receptor 4(CXCR4) Homo sapiens This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Gene Name: CXCR4
Protein Name: C-X-C chemokine receptor type 4
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分子量
- 39 kDa
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基因ID
- 7852
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OMIM
- 162643
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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