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DDIT3 抗体 (pSer30)

The 兔 多克隆 anti-DDIT3 antibody is suitable to detect DDIT3 in samples from 人 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN482168
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDIT3 抗体 (pSer30) (ABIN482168)

抗原

See all DDIT3 抗体
DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

适用

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人, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This DDIT3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 15-64, pSer30

    原理

    CHOP (phospho Ser30) Antibody

    特异性

    Phospho-CHOP (S30) Polyclonal Antibody detects endogenous levels of CHOP protein only when phosphorylated at S30.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CHOP around the phosphorylation site of Ser30. AA range:15-64

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

    别名

    CHOP

    背景

    Synonyms: DDIT3, CHOP, CHOP10, GADD153, DNA damage-inducible transcript 3 protein, DDIT-3, C/EBP-homologous protein, CHOP, C/EBP-homologous protein 10, CHOP-10, Growth arrest and DNA damage-inducible protein GADD153

    Background: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],

    Gene Name: DDIT3

    Protein Name: DNA damage-inducible transcript 3 protein

    分子量

    19 kDa

    基因ID

    1649

    OMIM

    126337

    UniProt

    P35638

    途径

    Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis
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