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Calmodulin 1 抗体 (pSer81, pThr79)

There is 1 publication for this product available. The 兔 多克隆 anti-Calmodulin 1 antibody is suitable to detect Calmodulin 1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1531529
发货至: 中国
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Quick Overview for Calmodulin 1 抗体 (pSer81, pThr79) (ABIN1531529)

抗原

See all Calmodulin 1 (CALM1) 抗体
Calmodulin 1 (CALM1)

适用

  • 105
  • 56
  • 42
  • 14
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
人, 大鼠, 小鼠

宿主

  • 109
  • 11
  • 1
兔

克隆类型

  • 90
  • 31
多克隆

标记

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  • 14
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Calmodulin 1 antibody is un-conjugated

应用范围

  • 88
  • 46
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  • 25
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  • 23
  • 20
  • 14
  • 14
  • 12
  • 5
  • 3
  • 3
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  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 13
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    • 9
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    • 1
    • 1
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    • 1
    AA 46-95, pSer81, pThr79

    原理

    Calmodulin-1 (phospho Thr80/S82) Antibody

    特异性

    Phospho-Calmodulin (T80/S82) Polyclonal Antibody detects endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Calmodulin-1 around the phosphorylation site of Thr79 and Ser81. AA range:46-95

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • Yokokura, Yurimoto, Matsuoka, Imataki, Dobashi, Bandoh, Matsunaga: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." in: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).

  • 抗原

    Calmodulin 1 (CALM1)

    别名

    Calmodulin

    背景

    Synonyms: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII, Calmodulin, CaM

    Background: This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

    Gene Name: CALM1

    Protein Name: Calmodulin-1

    分子量

    16 kDa

    基因ID

    801, 805, 808

    OMIM

    114180

    UniProt

    P0DP23

    途径

    cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling
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