Calmodulin 1 抗体 (pSer81, pThr79)
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Quick Overview for Calmodulin 1 抗体 (pSer81, pThr79) (ABIN1531529)
抗原
See all Calmodulin 1 (CALM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-95, pSer81, pThr79
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原理
- Calmodulin-1 (phospho Thr80/S82) Antibody
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特异性
- Phospho-Calmodulin (T80/S82) Polyclonal Antibody detects endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Calmodulin-1 around the phosphorylation site of Thr79 and Ser81. AA range:46-95
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." in: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).
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- Calmodulin 1 (CALM1)
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别名
- Calmodulin
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背景
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Synonyms: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII, Calmodulin, CaM
Background: This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],
Gene Name: CALM1
Protein Name: Calmodulin-1
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分子量
- 16 kDa
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基因ID
- 801, 805, 808
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OMIM
- 114180
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UniProt
- P0DP23
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途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling
抗原
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