p107 抗体 (pThr369)
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北京 101111
Quick Overview for p107 抗体 (pThr369) (ABIN1531517)
抗原
See all p107 (RBL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 335-384, pThr369
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原理
- p107 (phospho Thr369) Antibody
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特异性
- Phospho-p107 (T369) Polyclonal Antibody detects endogenous levels of p107 protein only when phosphorylated at T369.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RBL1 around the phosphorylation site of Thr369. AA range:335-384
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亚型
- IgG
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibody
RBL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibodyRBL1 适用: 人 WB, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 适用: 人, 小鼠, Cow, 马, Pig, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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别名
- RBL1
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背景
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Synonyms: RBL1, Retinoblastoma-like protein 1, 107 kDa retinoblastoma-associated protein, p107, pRb1
Background: The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought thatThe protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms hav
Gene Name: RBL1
Protein Name: Retinoblastoma-like protein 1
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分子量
- 120 kDa
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基因ID
- 5933
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OMIM
- 116957
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UniProt
- P28749
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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