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Actin 抗体 (pTyr53, pTyr55)

This 兔 多克隆 antibody specifically detects Actin in IHC, IF 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531480
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Actin 抗体 (pTyr53, pTyr55) (ABIN1531480)

抗原

See all Actin 抗体
Actin

适用

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人, 小鼠, 大鼠

宿主

  • 136
  • 44
  • 2
  • 1
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兔

克隆类型

  • 98
  • 86
多克隆

标记

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This Actin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    AA 21-70, pTyr53, pTyr55

    原理

    Actin-α/γ (phospho Tyr55/53) Antibody

    特异性

    Phospho-Actin-α/γ (Y55/53) Polyclonal Antibody detects endogenous levels of Actin-α/γ protein only when phosphorylated at Y55/53.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Actin-pan around the phosphorylation site of Tyr55/53. AA range:21-70

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Actin

    背景

    Synonyms: ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTG1, ACTB, ACTG, Actin, cytoplasmic 2, Gamma-actin, ACTG2, ACTA3, ACTL3, ACTSG, Actin, gamma-enteric smooth muscle, Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin,

    Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others.The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],

    Gene Name: ACTC1

    Protein Name: Actin alpha cardiac muscle 1

    分子量

    41 kDa

    基因ID

    70, 71, 72

    OMIM

    102540

    UniProt

    P68032
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