Fc gamma RII (CD32) (AA 258-307), (pTyr292) 抗体
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Quick Overview for Fc gamma RII (CD32) (AA 258-307), (pTyr292) 抗体 (ABIN1531425)
抗原
See all Fc gamma RII (CD32) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 258-307, pTyr292
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原理
- CD32 (phospho Tyr292) Antibody
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特异性
- Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Fc gamma RII (CD32)
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别名
- CD32
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背景
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Synonyms: FCGR2B, CD32, FCG2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD antigen CD32
Background: The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Gene Name: FCGR2B
Protein Name: Low affinity immunoglobulin gamma Fc region receptor II-b
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分子量
- 34 kDa
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基因ID
- 2213
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OMIM
- 604590
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UniProt
- P31994
抗原
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