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Fc gamma RII (CD32) (AA 258-307), (pTyr292) 抗体

The 兔 多克隆 anti-Fc gamma RII antibody (ABIN1531425) specifically detects Fc gamma RII in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1531425
发货至: 中国
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Quick Overview for Fc gamma RII (CD32) (AA 258-307), (pTyr292) 抗体 (ABIN1531425)

抗原

See all Fc gamma RII (CD32) 抗体
Fc gamma RII (CD32)

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

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  • 5
多克隆

标记

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非结合性

应用范围

  • 99
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 258-307, pTyr292

    原理

    CD32 (phospho Tyr292) Antibody

    特异性

    Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Fc gamma RII (CD32)

    别名

    CD32

    背景

    Synonyms: FCGR2B, CD32, FCG2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD antigen CD32

    Background: The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

    Gene Name: FCGR2B

    Protein Name: Low affinity immunoglobulin gamma Fc region receptor II-b

    分子量

    34 kDa

    基因ID

    2213

    OMIM

    604590

    UniProt

    P31994
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