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TNNI3 抗体 (pSer22, pSer23)

This 兔 多克隆 antibody specifically detects TNNI3 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN1531404
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TNNI3 抗体 (pSer22, pSer23) (ABIN1531404)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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小鼠, 大鼠

宿主

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  • 9
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  • 1
  • 1
兔

克隆类型

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多克隆

标记

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This TNNI3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
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    AA 5-54, pSer22, pSer23

    原理

    Troponin I-C (phospho Ser22/S23) Antibody

    特异性

    Phospho-Troponin I-C (S22/S23) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S22/S23.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from mouse TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    TNNI3

    背景

    Synonyms: TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I

    Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac.This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

    Gene Name: Tnni3

    Protein Name: Troponin I cardiac muscle

    分子量

    24 kDa

    UniProt

    P19429
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