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GTF2I 抗体 (pTyr248)

This 兔 多克隆 antibody specifically detects GTF2I in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531401
发货至: 中国
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Quick Overview for GTF2I 抗体 (pTyr248) (ABIN1531401)

抗原

See all GTF2I 抗体
GTF2I (General Transcription Factor III (GTF2I))

适用

  • 68
  • 34
  • 28
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 60
  • 8
兔

克隆类型

  • 50
  • 18
多克隆

标记

  • 42
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This GTF2I antibody is un-conjugated

应用范围

  • 52
  • 25
  • 24
  • 21
  • 12
  • 9
  • 9
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-263, pTyr248

    原理

    TFII-I (phospho Tyr248) Antibody

    特异性

    Phospho-TFII-I (Y248) Polyclonal Antibody detects endogenous levels of TFII-I protein only when phosphorylated at Y248.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human TFII-I around the phosphorylation site of Tyr248. AA range:214-263

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GTF2I (General Transcription Factor III (GTF2I))

    别名

    TFII-I

    背景

    Synonyms: GTF2I, BAP135, WBSCR6, General transcription factor II-I, GTFII-I, TFII-I, Bruton tyrosine kinase-associated protein 135, BAP-135, BTK-associated protein 135, SRF-Phox1-interacting protein, SPIN, Williams-Beuren syndrome chromosomal region

    Background: general transcription factor IIi(GTF2I) Homo sapiens This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013],

    Gene Name: GTF2I

    Protein Name: General transcription factor II-I

    分子量

    112 kDa

    基因ID

    2969

    OMIM

    194050

    UniProt

    P78347
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