GTF2I 抗体 (pTyr248)
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北京 101111
Quick Overview for GTF2I 抗体 (pTyr248) (ABIN1531401)
抗原
See all GTF2I 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 214-263, pTyr248
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原理
- TFII-I (phospho Tyr248) Antibody
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特异性
- Phospho-TFII-I (Y248) Polyclonal Antibody detects endogenous levels of TFII-I protein only when phosphorylated at Y248.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TFII-I around the phosphorylation site of Tyr248. AA range:214-263
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GTF2I (General Transcription Factor III (GTF2I))
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别名
- TFII-I
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背景
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Synonyms: GTF2I, BAP135, WBSCR6, General transcription factor II-I, GTFII-I, TFII-I, Bruton tyrosine kinase-associated protein 135, BAP-135, BTK-associated protein 135, SRF-Phox1-interacting protein, SPIN, Williams-Beuren syndrome chromosomal region
Background: general transcription factor IIi(GTF2I) Homo sapiens This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013],
Gene Name: GTF2I
Protein Name: General transcription factor II-I
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分子量
- 112 kDa
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基因ID
- 2969
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OMIM
- 194050
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UniProt
- P78347
抗原
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